β3 Integrin Promotes TGF-β1/H2O2/HOCl-Mediated Induction of Metastatic Phenotype of Hepatocellular Carcinoma Cells by Enhancing TGF-β1 Signaling

In addition to being an important mediator of migration and invasion of tumor cells, β3 integrin can also enhance TGF-β1 signaling. However, it is not known whether β3 might influence the induction of metastatic phenotype of tumor cells, especially non-metastatic tumor cells which express low level...

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Bibliographic Details
Main Authors: Feng, Xin-Xia, Liu, Mei, Yan, Wei, Zhou, Zhen-Zhen, Xia, Yu-Jia, Tu, Wei, Li, Pei-Yuan, Tian, De-An
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832483/