IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis

Inflammation-associated pigmentation changes are extremely common, but the etiology behind this clinical observation remains elusive. Particularly, it is unclear how the myriad of cytokines known to be involved in inflammatory skin processes affect epidermal melanocytes. We sought to determine how I...

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Bibliographic Details
Main Authors: Wang, Claire Q.F., Akalu, Yemscratch T., Suarez-Farinas, Mayte, Gonzalez, Juana, Mitsui, Hiroshi, Lowes, Michelle A., Orlow, Seth J., Manga, Prashiela, Krueger, James G.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830693/