Interleukin-33 overexpression is associated with liver fibrosis in mice and humans

Interleukin-33 (IL-33), the most recently identified member of the IL-1 family, induces synthesis of T Helper 2 (Th2)-type cytokines via its heterodimeric ST2/IL-1RAcP receptor. Th2-type cytokines play an important role in fibrosis; thus, we investigated the role of IL-33 in liver fibrosis. IL-33, S...

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Bibliographic Details
Main Authors: Marvie, Pierrick, Lisbonne, Mariette, L’Helgoualc’h, Annie, Rauch, Michel, Turlin, Bruno, Preisser, Laurence, Bourd-Boittin, Katia, Théret, Nathalie, Gascan, Hugues, Piquet-Pellorce, Claire, Samson, Michel
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829034/