Interleukin-33 overexpression is associated with liver fibrosis in mice and humans
Interleukin-33 (IL-33), the most recently identified member of the IL-1 family, induces synthesis of T Helper 2 (Th2)-type cytokines via its heterodimeric ST2/IL-1RAcP receptor. Th2-type cytokines play an important role in fibrosis; thus, we investigated the role of IL-33 in liver fibrosis. IL-33, S...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2010
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829034/ |