Deletion of the α-(1,3)-Glucan Synthase Genes Induces a Restructuring of the Conidial Cell Wall Responsible for the Avirulence of Aspergillus fumigatus

α-(1,3)-Glucan is a major component of the cell wall of Aspergillus fumigatus, an opportunistic human fungal pathogen. There are three genes (AGS1, AGS2 and AGS3) controlling the biosynthesis of α-(1,3)-glucan in this fungal species. Deletion of all the three AGS genes resulted in a triple mutant th...

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Bibliographic Details
Main Authors: Beauvais, Anne, Bozza, Silvia, Kniemeyer, Olaf, Formosa, Céline, Balloy, Viviane, Henry, Christine, Roberson, Robert W., Dague, Etienne, Chignard, Michel, Brakhage, Axel A., Romani, Luigina, Latgé, Jean-Paul
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828178/