Oct4 Is Required ∼E7.5 for Proliferation in the Primitive Streak

Oct4 Is Required ∼E7.5 for Proliferation in the Primitive Streak

Oct4 is a widely recognized pluripotency factor as it maintains Embryonic Stem (ES) cells in a pluripotent state, and, in vivo, prevents the inner cell mass (ICM) in murine embryos from differentiating into trophectoderm. However, its function in somatic tissue after this developmental stage is not...

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Main Authors: DeVeale, Brian, Brokhman, Irina, Mohseni, Paria, Babak, Tomas, Yoon, Charles, Lin, Anthony, Onishi, Kento, Tomilin, Alexey, Pevny, Larysa, Zandstra, Peter W., Nagy, Andras, van der Kooy, Derek
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828132/

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