Use of a Biomarker in Exposure–Response Analysis to Support Dose Selection for Fingolimod

Fingolimod 0.5 mg q.d. (once daily) has been approved for the treatment of patients with relapsing and remitting forms of multiple sclerosis (RRMS). Fingolimod at two doses (0.5 and 1.25 mg) showed superior effectiveness in the frequency of relapse with little difference between the two dose groups....

Full description

Bibliographic Details
Main Authors: Lee, J-Y, Wang, Y
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828008/