Targeted Gene Therapy of Xeroderma Pigmentosum Cells Using Meganuclease and TALEN™

Targeted Gene Therapy of Xeroderma Pigmentosum Cells Using Meganuclease and TALEN™

Xeroderma pigmentosum group C (XP-C) is a rare human syndrome characterized by hypersensitivity to UV light and a dramatic predisposition to skin neoplasms. XP-C cells are deficient in the nucleotide excision repair (NER) pathway, a complex process involved in the recognition and removal of DNA lesi...

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Bibliographic Details
Main Authors: Dupuy, Aurélie, Valton, Julien, Leduc, Sophie, Armier, Jacques, Galetto, Roman, Gouble, Agnès, Lebuhotel, Céline, Stary, Anne, Pâques, Frédéric, Duchateau, Philippe, Sarasin, Alain, Daboussi, Fayza
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827243/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827243/

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