Alzheimer's Disease Risk Assessment Using Large-Scale Machine Learning Methods

The goal of this work is to introduce new metrics to assess risk of Alzheimer's disease (AD) which we call AD Pattern Similarity (AD-PS) scores. These metrics are the conditional probabilities modeled by large-scale regularized logistic regression. The AD-PS scores derived from structural MRI a...

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Bibliographic Details
Main Authors: Casanova, Ramon, Hsu, Fang-Chi, Sink, Kaycee M., Rapp, Stephen R., Williamson, Jeff D., Resnick, Susan M., Espeland, Mark A.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826736/