SPIN90 dephosphorylation is required for cofilin-mediated actin depolymerization in NMDA-stimulated hippocampal neurons

Actin plays a fundamental role in the regulation of spine morphology (both shrinkage and enlargement) upon synaptic activation. In particular, actin depolymerization is crucial for the spine shrinkage in NMDAR-mediated synaptic depression. Here, we define the role of SPIN90 phosphorylation/dephospho...

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Bibliographic Details
Main Authors: Cho, In Ha, Lee, Min Jung, Kim, Dae Hwan, Kim, Bora, Bae, Jeomil, Choi, Kyu Yeong, Kim, Seon-Myung, Huh, Yun Hyun, Lee, Kun Ho, Kim, Chong-Hyun, Song, Woo Keun
Format: Online
Language:English
Published: Springer Basel 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825632/