Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma

Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma

Programmed cell death 4 (PDCD4), a novel tumor suppressor, inhibits cell proliferation, migration and invasion as well as promotes cell apoptosis in tumors. However, the molecular mechanism of its tumor-suppressive function remains largely unknown in tumors including nasopharyngeal carcinoma (NPC)....

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Bibliographic Details
Main Authors: Zhen, Yan, Liu, Zhen, Yang, Huiling, Yu, Xiaoli, Wu, Qiangyun, Hua, Shengni, Long, Xiaobin, Jiang, Qingping, Song, Ye, Cheng, Chao, Wang, Hao, Zhao, Menyang, Fu, Qiaofen, Lyu, Xiaoming, Chen, Yiyu, Fan, Yue, Liu, Yan, Li, Xin, Fang, Weiyi
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824685/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824685/

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