A Hidden Role of the Inactivated FANCD2: Upregulating ΔNp63
A compromised Fanconi Anemia (FA) signaling pathway, often resulting from an inactivated FANCD2, was recently recognized to contribute to the development of non-FA human tumors. However, it is largely unknown as to how an impaired FA pathway or an inactivated FANCD2 promotes tumorigenesis. Here we u...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Impact Journals LLC
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824532/ |