Affinity and catalytic heterogeneity of polyclonal myelin basic protein-hydrolyzing IgGs from sera of patients with multiple sclerosis

Affinity and catalytic heterogeneity of polyclonal myelin basic protein-hydrolyzing IgGs from sera of patients with multiple sclerosis

Human myelin basic protein (hMBP)-hydrolyzing activity was recently shown to be an intrinsic property of antibodies (Abs) from multiple sclerosis (MS) patients. Here, we present the first evidence demonstrating a significant diversity of different fractions of polyclonal IgGs (pIgGs) from MS patient...

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Bibliographic Details
Main Authors: Legostaeva, Galina A, Polosukhina, Dar’ya I, Bezuglova, Anna M, Doronin, Boris M, Buneva, Valentina N, Nevinsky, Georgy A
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823467/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823467/

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