Molecular Epidemiology and Evolution of West Nile Virus in North America
West Nile virus (WNV) was introduced to New York in 1999 and rapidly spread throughout North America and into parts of Central and South America. Displacement of the original New York (NY99) genotype by the North America/West Nile 2002 (NA/WN02) genotype occurred in 2002 with subsequent identificati...
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| Format: | Online |
| Language: | English |
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MDPI
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823310/ |
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pubmed-38233102013-11-11 Molecular Epidemiology and Evolution of West Nile Virus in North America Mann, Brian R. McMullen, Allison R. Swetnam, Daniele M. Barrett, Alan D. T. Review West Nile virus (WNV) was introduced to New York in 1999 and rapidly spread throughout North America and into parts of Central and South America. Displacement of the original New York (NY99) genotype by the North America/West Nile 2002 (NA/WN02) genotype occurred in 2002 with subsequent identification of a novel genotype in 2003 in isolates collected from the southwestern Unites States region (SW/WN03 genotype). Both genotypes co-circulate to date. Subsequent WNV surveillance studies have confirmed additional genotypes in the United States that have become extinct due to lack of a selective advantage or stochastic effect; however, the dynamic emergence, displacement, and extinction of multiple WNV genotypes in the US from 1999–2012 indicates the continued evolution of WNV in North America. MDPI 2013-10-16 2013-10 /pmc/articles/PMC3823310/ /pubmed/24135819 http://dx.doi.org/10.3390/ijerph10105111 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Mann, Brian R. McMullen, Allison R. Swetnam, Daniele M. Barrett, Alan D. T. |
| spellingShingle |
Mann, Brian R. McMullen, Allison R. Swetnam, Daniele M. Barrett, Alan D. T. Molecular Epidemiology and Evolution of West Nile Virus in North America |
| author_facet |
Mann, Brian R. McMullen, Allison R. Swetnam, Daniele M. Barrett, Alan D. T. |
| author_sort |
Mann, Brian R. |
| title |
Molecular Epidemiology and Evolution of West Nile Virus in North America |
| title_short |
Molecular Epidemiology and Evolution of West Nile Virus in North America |
| title_full |
Molecular Epidemiology and Evolution of West Nile Virus in North America |
| title_fullStr |
Molecular Epidemiology and Evolution of West Nile Virus in North America |
| title_full_unstemmed |
Molecular Epidemiology and Evolution of West Nile Virus in North America |
| title_sort |
molecular epidemiology and evolution of west nile virus in north america |
| description |
West Nile virus (WNV) was introduced to New York in 1999 and rapidly spread throughout North America and into parts of Central and South America. Displacement of the original New York (NY99) genotype by the North America/West Nile 2002 (NA/WN02) genotype occurred in 2002 with subsequent identification of a novel genotype in 2003 in isolates collected from the southwestern Unites States region (SW/WN03 genotype). Both genotypes co-circulate to date. Subsequent WNV surveillance studies have confirmed additional genotypes in the United States that have become extinct due to lack of a selective advantage or stochastic effect; however, the dynamic emergence, displacement, and extinction of multiple WNV genotypes in the US from 1999–2012 indicates the continued evolution of WNV in North America. |
| publisher |
MDPI |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823310/ |
| _version_ |
1612025332218462208 |