Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis

Vascular endothelium lines the entire cardiovascular system where performs a series of vital functions including the control of microvascular permeability, coagulation inflammation, vascular tone as well as the formation of new vessels via vasculogenesis and angiogenesis in normal and disease states...

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Main Author: Stan, RV
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823246/
id pubmed-3823246
recordtype oai_dc
spelling pubmed-38232462015-04-27 Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis Stan, RV Reviews Vascular endothelium lines the entire cardiovascular system where performs a series of vital functions including the control of microvascular permeability, coagulation inflammation, vascular tone as well as the formation of new vessels via vasculogenesis and angiogenesis in normal and disease states. Normal endothelium consists of heterogeneous populations of cells differentiated according to the vascular bed and segment of the vascular tree where they occur. One of the cardinal features is the expression of specific subcellular structures such as plas-malemmal vesicles or caveolae, transendothelial channels, vesiculo-vacuolar organelles, endothelial pockets and fenestrae, whose presence define several endothelial morphological types. A less explored observation is the differential expression of such structures in diverse settings of angiogenesis. This review will focus on the latest developments on the components, structure and function of these specific endothelial structures in normal endothelium as well as in diverse settings of angiogenesis. Blackwell Publishing Ltd 2007-07 2007-07-02 /pmc/articles/PMC3823246/ /pubmed/17760829 http://dx.doi.org/10.1111/j.1582-4934.2007.00075.x Text en
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Stan, RV
spellingShingle Stan, RV
Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
author_facet Stan, RV
author_sort Stan, RV
title Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
title_short Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
title_full Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
title_fullStr Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
title_full_unstemmed Endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
title_sort endothelial stomatal and fenestral diaphragms in normal vessels and angiogenesis
description Vascular endothelium lines the entire cardiovascular system where performs a series of vital functions including the control of microvascular permeability, coagulation inflammation, vascular tone as well as the formation of new vessels via vasculogenesis and angiogenesis in normal and disease states. Normal endothelium consists of heterogeneous populations of cells differentiated according to the vascular bed and segment of the vascular tree where they occur. One of the cardinal features is the expression of specific subcellular structures such as plas-malemmal vesicles or caveolae, transendothelial channels, vesiculo-vacuolar organelles, endothelial pockets and fenestrae, whose presence define several endothelial morphological types. A less explored observation is the differential expression of such structures in diverse settings of angiogenesis. This review will focus on the latest developments on the components, structure and function of these specific endothelial structures in normal endothelium as well as in diverse settings of angiogenesis.
publisher Blackwell Publishing Ltd
publishDate 2007
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823246/
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