The therapeutic effect of Rosuvastatin on cardiac remodelling from hypertrophy to fibrosis during the end-stage hypertension in rats

End-stage hypertensive heart disease is an increasing cause of cardiac mortality. Therefore, the current study focused on the cardiac remodelling from hypertrophy to fibrosis in old-aged spontaneously hypertensive rats (SHRs), and explored the therapeutic effects of Rosuvastatin and its possible mec...

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Bibliographic Details
Main Authors: Zhang, WB, Du, QJ, Li, H, Sun, AJ, Qiu, ZH, Wu, CN, Zhao, G, Gong, H, Hu, K, Zou, YZ, Ge, JB
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822992/