Immunogenicity of allogeneic mesenchymal stem cells

Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion molecule-1 (VCAM-1). We investigated whether their immunosuppressive properties and low immunophenotype protect allogeneic...

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Bibliographic Details
Main Authors: Schu, Sabine, Nosov, Mikhail, O'Flynn, Lisa, Shaw, Georgina, Treacy, Oliver, Barry, Frank, Murphy, Mary, O'Brien, Timothy, Ritter, Thomas
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822979/