Secretory products of guinea pig epicardial fat induce insulin resistance and impair primary adult rat cardiomyocyte function

Epicardial adipose tissue (EAT) has been implicated in the development of heart disease. Nonetheless, the crosstalk between factors secreted from EAT and cardiomyocytes has not been studied. Here, we examined the effect of factors secreted from EAT on contractile function and insulin signalling in p...

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Bibliographic Details
Main Authors: Greulich, Sabrina, de Wiza, Daniella Herzfeld, Preilowski, Sebastian, Ding, Zhaoping, Mueller, Heidi, Langin, Dominique, Jaquet, Kornelia, Ouwens, D Margriet, Eckel, Juergen
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822951/