Activators and inhibitors of the plasminogen system in Alzheimer’s disease
Accumulation and deposition of Aβ is one of the main neuropathological hallmarks of Alzheimer’s disease (AD) and impaired Aβ degradation may be one mechanism of accumulation. Plasmin is the key protease of the plasminogen system and can cleave Aβ. Plasmin is activated from plasminogen by tissue plas...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Blackwell Publishing Ltd
2012
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822855/ |