Ox-LDL modifies the behaviour of bone marrow stem cells and impairs their endothelial differentiation via inhibition of Akt phosphorylation

This study was to investigate the effect of oxidized low-density lipoprotein (ox-LDL) on the behaviour of bone marrow stem cells and their endothelial differentiation as well as the underlying mechanisms. Adult rat bone marrow multipotent progenitor cells (MAPCs) were incubated with ox-LDL for up to...

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Bibliographic Details
Main Authors: Chu, Ling, Hao, Hong, Luo, Min, Huang, Yu, Chen, Zhenyu, Lu, Tiewei, Zhao, Xue, Verfaillie, Catherine M, Zweier, Jay L, Liu, Zhenguo
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822806/