Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice

Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice

Anti-angiogenesis represents a promising therapeutic strategy for the treatment of various malignancies. Isthmin (ISM) is a gene highly expressed in the isthmus of the midbrain–hindbrain organizer in Xenopus with no known functions. It encodes a secreted 60 kD protein containing a thrombospondin typ...

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Bibliographic Details
Main Authors: Xiang, Wei, Ke, Zhiyuan, Zhang, Yong, Ho-Yuet Cheng, Grace, Irwan, Ishak Darryl, Sulochana, K N, Potturi, Padma, Wang, Zhengyuan, Yang, He, Wang, Jingyu, Zhuo, Lang, Kini, R Manjunatha, Ge, Ruowen
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822802/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822802/

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