Antigen-Specific T-Cell Activation Independently of the MHC: Chimeric Antigen Receptor-Redirected T Cells
Adoptive T-cell therapy has recently shown promise in initiating a lasting anti-tumor response with spectacular therapeutic success in some cases. Specific T-cell therapy, however, is limited since a number of cancer cells are not recognized by T cells due to various mechanisms including the limited...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822734/ |