The unfolded protein response in hereditary haemochromatosis

To cope with the accumulation of unfolded or misfolded proteins the endoplasmic reticulum (ER) has evolved specific signalling pathways collectively called the unfolded protein response (UPR). Elucidation of the mechanisms governing ER stress signallinghas linked this response to the regulation of d...

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Bibliographic Details
Main Authors: De Almeida, SF, De Sousa, M
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822533/