Reduction of influenza virus-induced lung inflammation and mortality in animals treated with a phosophodisestrase-4 inhibitor and a selective serotonin reuptake inhibitor

Inflammatory responses contribute to the morbidity and mortality of severe influenza. Current antiviral therapy offers limited success in treating severe influenza infection with both H1N1 and H5N1 viruses. We evaluated the effect of a neuraminidase inhibitor in combination with immunomodulatory dru...

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Bibliographic Details
Main Authors: Sharma, Geeta, Champalal Sharma, Danilal, Hwei Fen, Leong, Pathak, Mukta, Bethur, Nijaguna, Pendharkar, Vishal, Peiris, Malik, Altmeyer, Ralf
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821288/