The Cytotoxic Necrotizing Factor of Yersinia pseudotuberculosis (CNFY) Enhances Inflammation and Yop Delivery during Infection by Activation of Rho GTPases

Some isolates of Yersinia pseudotuberculosis produce the cytotoxic necrotizing factor (CNFY), but the functional consequences of this toxin for host-pathogen interactions during the infection are unknown. In the present study we show that CNFY has a strong influence on virulence. We demonstrate that...

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Bibliographic Details
Main Authors: Schweer, Janina, Kulkarni, Devesha, Kochut, Annika, Pezoldt, Joern, Pisano, Fabio, Pils, Marina C., Genth, Harald, Huehn, Jochen, Dersch, Petra
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820761/