The Homeobox Gene MEIS1 Is Methylated in BRAF p.V600E Mutated Colon Tumors

Development of colorectal cancer (CRC) can occur both via gene mutations in tumor suppressor genes and oncogenes, as well as via epigenetic changes, including DNA methylation. Site-specific methylation in CRC regulates expression of tumor-associated genes. Right-sided colon tumors more frequently ha...

Full description

Bibliographic Details
Main Authors: Dihal, Ashwin A., Boot, Arnoud, van Roon, Eddy H., Schrumpf, Melanie, Fariña-Sarasqueta, Arantza, Fiocco, Marta, Zeestraten, Eliane C. M., Kuppen, Peter J. K., Morreau, Hans, van Wezel, Tom, Boer, Judith M.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820613/