A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide

A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide

The gut barrier, composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, prevents the entrance of harmful microorganisms, antigens and toxins from the gut lumen into the blood. Small intestinal homeostasis is normally maintained by the rate of shedding of s...

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Bibliographic Details
Main Authors: Williams, Jonathan M., Duckworth, Carrie A., Watson, Alastair J. M., Frey, Mark R., Miguel, Jennifer C., Burkitt, Michael D., Sutton, Robert, Hughes, Kevin R., Hall, Lindsay J., Caamaño, Jorge H., Campbell, Barry J., Pritchard, D. Mark
Format: Online
Language:English
Published: The Company of Biologists Limited 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820262/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820262/

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