Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice
Lipid disorders pose therapeutic challenges. Previously we discovered that mutation of the hepatocyte β-hydroxybutyrate transporter Slc16a6a in zebrafish causes hepatic steatosis during fasting, marked by increased hepatic triacylglycerol, but not cholesterol. This selective diversion of trapped ket...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Company of Biologists Limited
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820260/ |