Monotonicity is a key feature of genotype-phenotype maps

It was recently shown that monotone gene action, i.e., order-preservation between allele content and corresponding genotypic values in the mapping from genotypes to phenotypes, is a prerequisite for achieving a predictable parent-offspring relationship across the whole allele frequency spectrum. Her...

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Bibliographic Details
Main Authors: Gjuvsland, Arne B., Wang, Yunpeng, Plahte, Erik, Omholt, Stig W.
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819525/