TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes

RING (Really Interesting New Gene)-in-between-RING (RBR) enzymes are a distinct class of E3 ubiquitin ligases possessing a cluster of three zinc-binding domains that cooperate to catalyse ubiquitin transfer. The regulation and biological function for most members of the RBR ligases is not known, and...

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Main Authors: Kelsall, Ian R, Duda, David M, Olszewski, Jennifer L, Hofmann, Kay, Knebel, Axel, Langevin, Frédéric, Wood, Nicola, Wightman, Melanie, Schulman, Brenda A, Alpi, Arno F
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817463/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817463/

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