Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo

Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo

Estrogen receptor (ER)-β has been shown to possess a tumor suppressive effect, and is a potential target for cancer therapy. Using gene-expression meta-analysis of human malignant pleural mesothelioma, we identified an ESR2 (ERβ coding gene) signature. High ESR2 expression was strongly associated wi...

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Bibliographic Details
Main Authors: Manente, A G, Valenti, D, Pinton, G, Jithesh, P V, Daga, A, Rossi, L, Gray, S G, O'Byrne, K J, Fennell, D A, Vacca, R A, Nilsson, S, Mutti, L, Moro, L
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816222/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816222/

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