Bioengineered nisin derivatives with enhanced activity in complex matrices

Nisin A is the best known and most extensively characterized lantibiotic. As it is ribosomally synthesized, bioengineering‐based strategies can be used to generate variants. We have previously demonstrated that bioengineering of the hinge region of nisin A can result in the generation of variants wi...

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Bibliographic Details
Main Authors: Rouse, Susan, Field, Des, Daly, Karen M., O'Connor, Paula M., Cotter, Paul D., Hill, Colin, Ross, R. Paul
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815327/