Agonist Antagonist Interactions at the Rapidly Desensitizing P2X3 Receptor

P2X3 receptors (P2XRs), as members of the purine receptor family, are deeply involved in chronic pain sensation and therefore, specific, competitive antagonists are of great interest for perspective pain management. Heretofore, Schild plot analysis has been commonly used for studying the interaction...

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Bibliographic Details
Main Authors: Helms, Nick, Kowalski, Maria, Illes, Peter, Riedel, Thomas
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815160/