Automated Detection of Systematic Off-label Drug Use in Free Text of Electronic Medical Records

Off-label use of a drug occurs when it is used in a manner that deviates from its FDA label. Studies estimate that 21% of prescriptions are off-label, with only 27% of those uses supported by evidence of safety and efficacy. We have developed methods to detect population level off-label usage using...

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Bibliographic Details
Main Authors: Jung, Kenneth, LePendu, Paea, Shah, Nigam
Format: Online
Language:English
Published: American Medical Informatics Association 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814472/