Bidirectional Best Hits Miss Many Orthologs in Duplication-Rich Clades such as Plants and Animals

Bidirectional best hits (BBH), which entails identifying the pairs of genes in two different genomes that are more similar to each other than either is to any other gene in the other genome, is a simple and widely used method to infer orthology. A recent study has analyzed the link between BBH and o...

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Bibliographic Details
Main Authors: Dalquen, Daniel A., Dessimoz, Christophe
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814191/