Suppression of metastasis of human pancreatic cancer cells to the liver by small interfering RNA-mediated targeting of the midkine gene

The present study aimed to ascertain whether suppression of midkine (MK) expression in pancreatic cancer cells inhibits metastasis to the liver. Human pancreatic cancer AsPC-1 cells were transfected with small interfering RNA (siRNA) targeting MK. siRNA against MK was observed to reduce the expressi...

Full description

Bibliographic Details
Main Authors: YU, LI, FAN, YU, CHEN, BAODING, HU, YUE, GAO, YINA, WEI, DA
Format: Online
Language:English
Published: D.A. Spandidos 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813521/