Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

Hydrochlorothiazide (HCTZ) is one of the most widely prescribed antihypertensive medications. Although it is well known that HCTZ is associated with hyperglycemia and hypertriglyceridemia, the mechanisms underlying these adverse effects are not well understood. We performed a genome-wide association...

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Bibliographic Details
Main Authors: Del-Aguila, J L, Beitelshees, A L, Cooper-DeHoff, R M, Chapman, A B, Gums, J G, Bailey, K, Gong, Y, Turner, S T, Johnson, J A, Boerwinkle, E
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812324/