Impact of Sequence Variation in the UL128 Locus on Production of Human Cytomegalovirus in Fibroblast and Epithelial Cells

The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A. UL128L is necessary for efficient infection of myeloid, epithelial, and endothelial cells but limits replication i...

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Bibliographic Details
Main Authors: Murrell, Isa, Tomasec, Peter, Wilkie, Gavin S., Dargan, Derrick J., Davison, Andrew J., Stanton, Richard J.
Format: Online
Language:English
Published: American Society for Microbiology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807394/