Cellular network entropy as the energy potential in Waddington's differentiation landscape

Differentiation is a key cellular process in normal tissue development that is significantly altered in cancer. Although molecular signatures characterising pluripotency and multipotency exist, there is, as yet, no single quantitative mark of a cellular sample's position in the global different...

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Bibliographic Details
Main Authors: Banerji, Christopher R. S., Miranda-Saavedra, Diego, Severini, Simone, Widschwendter, Martin, Enver, Tariq, Zhou, Joseph X., Teschendorff, Andrew E.
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807110/