Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome

Characterization of the pattern of clonal evolution from CLL to RS, the genetic determinants of CLL transformation to RS, and the pathogenetic relationship between RS and classical non–CLL-associated de novo DLBCL.

Bibliographic Details
Main Authors: Fabbri, Giulia, Khiabanian, Hossein, Holmes, Antony B., Wang, Jiguang, Messina, Monica, Mullighan, Charles G., Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804949/
Description
Summary:Characterization of the pattern of clonal evolution from CLL to RS, the genetic determinants of CLL transformation to RS, and the pathogenetic relationship between RS and classical non–CLL-associated de novo DLBCL.