Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance

Cross talk between Wnt and IFN signaling determines the development of CML-leukemia–initiating cells and represents a mechanism for the acquisition of resistance to Imatinib at later stages of CML.

Bibliographic Details
Main Authors: Scheller, Marina, Schönheit, Jörg, Zimmermann, Karin, Leser, Ulf, Rosenbauer, Frank, Leutz, Achim
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804946/