Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

The CXCR4 antagonist plerixafor augments frequency of circulating neutrophils via release from the lung and prevents neutrophil homing to the bone marrow.

Bibliographic Details
Main Authors: Devi, Sapna, Wang, Yilin, Chew, Weng Keong, Lima, Ronald, A-González, Noelia, Mattar, Citra N.Z., Chong, Shu Zhen, Schlitzer, Andreas, Bakocevic, Nadja, Chew, Samantha, Keeble, Jo L., Goh, Chi Ching, Li, Jackson L.Y., Evrard, Maximilien, Malleret, Benoit, Larbi, Anis, Renia, Laurent, Haniffa, Muzlifah, Tan, Suet Mien, Chan, Jerry K.Y., Balabanian, Karl, Nagasawa, Takashi, Bachelerie, Françoise, Hidalgo, Andrés, Ginhoux, Florent, Kubes, Paul, Ng, Lai Guan
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804935/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804935/

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