Heterotrimeric G-Protein, Gα16, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer

Heterotrimeric G-Protein, Gα16, Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer

G-protein-coupled receptors (GPCR) are the largest family of cell surface molecules that play important role/s in a number of biological and pathological processes including cancers. Earlier studies have highlighted the importance of Wnt7a signaling via its cognate receptor Frizzled9, a GPCR, in inh...

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Bibliographic Details
Main Authors: Avasarala, Sreedevi, Bikkavilli, Rama Kamesh, Van Scoyk, Michelle, Zhang, Wei, Lapite, Ajibike, Hostetter, Logan, Byers, Joshua T., Heasley, Lynn E., Sohn, Jang Won, Winn, Robert A.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800035/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800035/

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