Antigen Presenting Cell-Mediated Expansion of Human Umbilical Cord Blood Yields Log-Scale Expansion of Natural Killer Cells with Anti-Myeloma Activity

Antigen Presenting Cell-Mediated Expansion of Human Umbilical Cord Blood Yields Log-Scale Expansion of Natural Killer Cells with Anti-Myeloma Activity

Natural killer (NK) cells are important mediators of anti-tumor immunity and are active against several hematologic malignancies, including multiple myeloma (MM). Umbilical cord blood (CB) is a promising source of allogeneic NK cells but large scale ex vivo expansion is required for generation of cl...

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Bibliographic Details
Main Authors: Shah, Nina, Martin-Antonio, Beatriz, Yang, Hong, Ku, Stephanie, Lee, Dean A., Cooper, Laurence J. N., Decker, William K., Li, Sufang, Robinson, Simon N., Sekine, Takuya, Parmar, Simrit, Gribben, John, Wang, Michael, Rezvani, Katy, Yvon, Eric, Najjar, Amer, Burks, Jared, Kaur, Indreshpal, Champlin, Richard E., Bollard, Catherine M., Shpall, Elizabeth J.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800010/

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