Cooperative Functions of ZnT1, Metallothionein and ZnT4 in the Cytoplasm Are Required for Full Activation of TNAP in the Early Secretory Pathway

The activation process of secretory or membrane-bound zinc enzymes is thought to be a highly coordinated process involving zinc transport, trafficking, transfer and coordination. We have previously shown that secretory and membrane-bound zinc enzymes are activated in the early secretory pathway (ESP...

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Bibliographic Details
Main Authors: Fujimoto, Shigeyuki, Itsumura, Naoya, Tsuji, Tokuji, Anan, Yasumi, Tsuji, Natsuko, Ogra, Yasumitsu, Kimura, Tomoki, Miyamae, Yusaku, Masuda, Seiji, Nagao, Masaya, Kambe, Taiho
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799634/