Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

Fetal alcohol spectrum disorder (FASD) occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic birth defects that include craniofacial, neural and cardiac defects. Gastrulation is a particularly sensitive developmental stage for teratogen exposure, and zeb...

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Bibliographic Details
Main Authors: Sarmah, Swapnalee, Muralidharan, Pooja, Curtis, Courtney L., McClintick, Jeanette N., Buente, Bryce B., Holdgrafer, David J., Ogbeifun, Osato, Olorungbounmi, Opeyemi C., Patino, Liliana, Lucas, Ryan, Gilbert, Sonya, Groninger, Evan S., Arciero, Julia, Edenberg, Howard J., Marrs, James A.
Format: Online
Language:English
Published: The Company of Biologists 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798184/