Different Involvement of Promoter Methylation in the Expression of Organic Cation/Carnitine Transporter 2 (OCTN2) in Cancer Cell Lines

Different Involvement of Promoter Methylation in the Expression of Organic Cation/Carnitine Transporter 2 (OCTN2) in Cancer Cell Lines

Organic cation/carnitine transporter 2 (OCTN2) is responsible for the cellular uptake of the antineoplastic agent, oxaliplatin. Epigenetic modification is a possible mechanism of altered drug-transporter expression in cancers, leading to altered efficacy of chemotherapeutic drugs. However, the mecha...

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Bibliographic Details
Main Authors: Qu, Qiang, Qu, Jian, Zhan, Min, Wu, Lan-Xiang, Zhang, Yi-Wen, Lou, Xiao-Ya, Fu, Li-Juan, Zhou, Hong-Hao
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797819/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797819/

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