Complex Patterns of Chromosome 11 Aberrations in Myeloid Malignancies Target CBL, MLL, DDB1 and LMO2
Exome sequencing of primary tumors identifies complex somatic mutation patterns. Assignment of relevance of individual somatic mutations is difficult and poses the next challenge for interpretation of next generation sequencing data. Here we present an approach how exome sequencing in combination wi...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797696/ |