Identification of Genes Potentially Regulated by Human Polynucleotide Phosphorylase (hPNPaseold-35) Using Melanoma as a Model
Human Polynucleotide Phosphorylase (hPNPaseold-35 or PNPT1) is an evolutionarily conserved 3′→5′ exoribonuclease implicated in the regulation of numerous physiological processes including maintenance of mitochondrial homeostasis, mtRNA import and aging-associated inflammation. From an RNase perspect...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797080/ |