The Long Noncoding RNA HOTAIR Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma Cells via downregualtion of p21WAF1/CIP1 Expression

HOTAIR, a long intervening non-coding RNA (lincRNA), associates with the Polycomb Repressive Complex 2 (PRC2) and is reported to reprogram chromatin organization and promote tumor progression. However, little is known about the roles of this gene in the development of chemoresistance phenotype of lu...

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Bibliographic Details
Main Authors: Liu, Zhili, Sun, Ming, Lu, Kaihua, Liu, Jing, Zhang, Meiling, Wu, Weiqin, De, Wei, Wang, Zhaoxia, Wang, Rui
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796503/