The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

The Electronic Medical Records and Genomics Network is a National Human Genome Research Institute–funded consortium engaged in the development of methods and best practices for using the electronic medical record as a tool for genomic research. Now in its sixth year and second funding cycle, and com...

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Main Authors: Gottesman, Omri, Kuivaniemi, Helena, Tromp, Gerard, Faucett, W. Andrew, Li, Rongling, Manolio, Teri A., Sanderson, Saskia C., Kannry, Joseph, Zinberg, Randi, Basford, Melissa A., Brilliant, Murray, Carey, David J., Chisholm, Rex L., Chute, Christopher G., Connolly, John J., Crosslin, David, Denny, Joshua C., Gallego, Carlos J., Haines, Jonathan L., Hakonarson, Hakon, Harley, John, Jarvik, Gail P., Kohane, Isaac, Kullo, Iftikhar J., Larson, Eric B., McCarty, Catherine, Ritchie, Marylyn D., Roden, Dan M., Smith, Maureen E., Böttinger, Erwin P., Williams, Marc S.
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795928/
id pubmed-3795928
recordtype oai_dc
spelling pubmed-37959282013-10-12 The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future Gottesman, Omri Kuivaniemi, Helena Tromp, Gerard Faucett, W. Andrew Li, Rongling Manolio, Teri A. Sanderson, Saskia C. Kannry, Joseph Zinberg, Randi Basford, Melissa A. Brilliant, Murray Carey, David J. Chisholm, Rex L. Chute, Christopher G. Connolly, John J. Crosslin, David Denny, Joshua C. Gallego, Carlos J. Haines, Jonathan L. Hakonarson, Hakon Harley, John Jarvik, Gail P. Kohane, Isaac Kullo, Iftikhar J. Larson, Eric B. McCarty, Catherine Ritchie, Marylyn D. Roden, Dan M. Smith, Maureen E. Böttinger, Erwin P. Williams, Marc S. Review The Electronic Medical Records and Genomics Network is a National Human Genome Research Institute–funded consortium engaged in the development of methods and best practices for using the electronic medical record as a tool for genomic research. Now in its sixth year and second funding cycle, and comprising nine research groups and a coordinating center, the network has played a major role in validating the concept that clinical data derived from electronic medical records can be used successfully for genomic research. Current work is advancing knowledge in multiple disciplines at the intersection of genomics and health-care informatics, particularly for electronic phenotyping, genome-wide association studies, genomic medicine implementation, and the ethical and regulatory issues associated with genomics research and returning results to study participants. Here, we describe the evolution, accomplishments, opportunities, and challenges of the network from its inception as a five-group consortium focused on genotype–phenotype associations for genomic discovery to its current form as a nine-group consortium pivoting toward the implementation of genomic medicine. Nature Publishing Group 2013-10 2013-06-06 /pmc/articles/PMC3795928/ /pubmed/23743551 http://dx.doi.org/10.1038/gim.2013.72 Text en Copyright © 2013 American College of Medical Genetics and Genomics http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Gottesman, Omri
Kuivaniemi, Helena
Tromp, Gerard
Faucett, W. Andrew
Li, Rongling
Manolio, Teri A.
Sanderson, Saskia C.
Kannry, Joseph
Zinberg, Randi
Basford, Melissa A.
Brilliant, Murray
Carey, David J.
Chisholm, Rex L.
Chute, Christopher G.
Connolly, John J.
Crosslin, David
Denny, Joshua C.
Gallego, Carlos J.
Haines, Jonathan L.
Hakonarson, Hakon
Harley, John
Jarvik, Gail P.
Kohane, Isaac
Kullo, Iftikhar J.
Larson, Eric B.
McCarty, Catherine
Ritchie, Marylyn D.
Roden, Dan M.
Smith, Maureen E.
Böttinger, Erwin P.
Williams, Marc S.
spellingShingle Gottesman, Omri
Kuivaniemi, Helena
Tromp, Gerard
Faucett, W. Andrew
Li, Rongling
Manolio, Teri A.
Sanderson, Saskia C.
Kannry, Joseph
Zinberg, Randi
Basford, Melissa A.
Brilliant, Murray
Carey, David J.
Chisholm, Rex L.
Chute, Christopher G.
Connolly, John J.
Crosslin, David
Denny, Joshua C.
Gallego, Carlos J.
Haines, Jonathan L.
Hakonarson, Hakon
Harley, John
Jarvik, Gail P.
Kohane, Isaac
Kullo, Iftikhar J.
Larson, Eric B.
McCarty, Catherine
Ritchie, Marylyn D.
Roden, Dan M.
Smith, Maureen E.
Böttinger, Erwin P.
Williams, Marc S.
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
author_facet Gottesman, Omri
Kuivaniemi, Helena
Tromp, Gerard
Faucett, W. Andrew
Li, Rongling
Manolio, Teri A.
Sanderson, Saskia C.
Kannry, Joseph
Zinberg, Randi
Basford, Melissa A.
Brilliant, Murray
Carey, David J.
Chisholm, Rex L.
Chute, Christopher G.
Connolly, John J.
Crosslin, David
Denny, Joshua C.
Gallego, Carlos J.
Haines, Jonathan L.
Hakonarson, Hakon
Harley, John
Jarvik, Gail P.
Kohane, Isaac
Kullo, Iftikhar J.
Larson, Eric B.
McCarty, Catherine
Ritchie, Marylyn D.
Roden, Dan M.
Smith, Maureen E.
Böttinger, Erwin P.
Williams, Marc S.
author_sort Gottesman, Omri
title The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
title_short The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
title_full The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
title_fullStr The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
title_full_unstemmed The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
title_sort electronic medical records and genomics (emerge) network: past, present, and future
description The Electronic Medical Records and Genomics Network is a National Human Genome Research Institute–funded consortium engaged in the development of methods and best practices for using the electronic medical record as a tool for genomic research. Now in its sixth year and second funding cycle, and comprising nine research groups and a coordinating center, the network has played a major role in validating the concept that clinical data derived from electronic medical records can be used successfully for genomic research. Current work is advancing knowledge in multiple disciplines at the intersection of genomics and health-care informatics, particularly for electronic phenotyping, genome-wide association studies, genomic medicine implementation, and the ethical and regulatory issues associated with genomics research and returning results to study participants. Here, we describe the evolution, accomplishments, opportunities, and challenges of the network from its inception as a five-group consortium focused on genotype–phenotype associations for genomic discovery to its current form as a nine-group consortium pivoting toward the implementation of genomic medicine.
publisher Nature Publishing Group
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795928/
_version_ 1612018080928497664

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